If you’re searching for everything about the San Francisco 49ers vs LA Rams NFL matchup—including Christian McCaffrey and Kyren Williams stats, schedules, how to watch live, key player updates, and score predictions—you’re in the right place. Here’s your ultimate SEO-friendly guide covering all the trending topics for today’s NFC West battle at SoFi Stadium.
Game Info: Where and When to Watch 49ers vs Rams
Matchup: SF 49ers vs Los Angeles Rams
Date: Thursday, October 2, 2025
Time: 8:15 p.m. ET / 5:15 p.m. PT
Venue: SoFi Stadium, Inglewood, CA
TV/Streaming: Amazon Prime Video (nationally), Local TV in LA/SF, NFL+ streaming app for mobile viewers
Thursday Night Football (TNF) Tonight: Yes, this is the featured TNF game for Week 5
Quick Team Stats & Record
Team | Record | Last Game | NFC West Ranking |
|---|---|---|---|
San Francisco 49ers | 3-1 | Lost vs Jaguars | 1st |
Los Angeles Rams | 3-1 | Won vs Colts | 3rd |
Key Player Stats & Injury Updates
Christian McCaffrey (49ers RB)
Season (4 games): 69 attempts, 225 rushing yards, 2 TDs, 31 receptions, 305 receiving yards
Career vs Rams: 101.8 rushing yards per game, 1 TD/game
Status: Healthy
Kyren Williams (Rams RB)
Season (4 games): 68 attempts, 303 rushing yards, 1 TD, 20 receptions, 327 receiving yards
Scored a key TD last week
Matthew Stafford (Rams QB)
Season (4 games): 92/136 passes, 1,114 yards, 8 TDs, 2 INTs
Status: Playing
49ers Injuries:
Brock Purdy (QB): Out, toe injury
Ricky Pearsall (WR): Out, knee injury
Jauan Jennings (WR): Out, ankle/rib
George Kittle (TE): Out, hamstring
Game Preview & Predictions
Both LA Rams and SF 49ers enter with 3-1 records, fighting for NFC West leadership.
Recent history favors the Rams, with a three-game win streak vs the Niners.
The Rams are favored by 8.5 points; predicted score: Rams 23 - 49ers 19. Experts pick the 49ers to cover if betting the spread, and the total points likely to stay under 44.5.
Head coaches: Kyle Shanahan (49ers) and Sean McVay (Rams) headline a strategic showdown.
Expect top performances from Kyren Williams and Matthew Stafford for LA, and Christian McCaffrey for San Francisco.
Blake Corum, Brian Robinson, and Marquez Valdes-Scantling are NOT featured in the primary lineups for this week.
How to Watch Thursday Night Football This Week
Amazon Prime Video: Exclusive national broadcast live. Free trial available for new viewers.
NFL+: Stream on mobile; subscription or free trial option.
Local TV: Simulcast in Los Angeles and San Francisco markets.
NFC West Standings Update
Rams, 49ers, and Seahawks are all fighting for first place as Week 5 begins.
This matchup may determine the divisional frontrunner!
Final Word: Who Will Win?
All major sports outlets predict a close divisional rumble. The Rams have the edge at home, but the 49ers’ playmaking on defense and Christian McCaffrey’s versatility keeps them in the hunt for an upset. Expect a physical, strategic game under the lights at SoFi Stadium!
